Z1

Histopathology Service

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Central project Z1 offers a histopathological service for experimental animal models.

Since the clinical phenotype in EAE and autoimmune optic neuritis, which are the models included into all of the projects, is determined by many different factors such as inflammation, demyelination and axonal injury, it is essential that a detailed histopathological analysis by quantitative technologies is included. This will be achieved both by performing analysis of retinas, optic nerve, brain and spinal cord tissue in direct collaboration with the involved partners and by training and education of the partners in histopathological analysis (conventional histology, immunocytochemistry and confocal laser microscopy) in the course of short scientific missions.